IL-6, Mouse Antibody from HYCULT BIOTECH

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Antigenic SpecificityIL-6, Mouse
CloneMP5-32C11
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a
Formatunconjugated
Size100 µg
Concentrationn/a
ApplicationsFunctional studies, Immuno assays, Immuno precipitation, Western blot. RUO
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DescriptionThe antibody neutralizes mouse interleukin 6 (IL-6). It does not cross-react with LPS (the component of the bacterial cell wall which is considered responsible for the toxicity of gram-negative bacteria) and TNFalpha nor does it block human or rat IL-6 in proliferation assays using the KD83 cell line. MP5-32C11 inhibits mouse IL-6-induced proliferation of the NFS60 myelomonocytic cell line and KD83 plasmacytoma. IL-6 is a pluripotent 20-22 kDa cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and haematopoiesis. IL-6 plays a critical role in Bcell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibodyproducing hybridomas.
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #HM1005-100UG
Price$325
Order / More InfoIL-6, Mouse Antibody from HYCULT BIOTECH
Product Specific Referencesn/a
HYCULT BIOTECH
HYCULT BIOTECH
HYCULT BIOTECH
Frontstraat 2a
5405 PB Uden THE NETHERLANDS
P: +31 (0)413 251335
F: +31 (0)413 248353

info@hycultbiotech.com

https://www.hycultbiotech.com

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