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Antigenic Specificity | CD44, Human |
Clone | NKI-P2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 100 µg |
Concentration | n/a |
Applications | Flow cytometry, Frozen sections, Paraffin sections. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD44, also designated Pgp-1 or H-CAM, is a broadly distributed 85 kD protein. Amongst haematopoietic cells CD44 is expressed on B and T lymphocytes, monocytes and neutrophils. Other CD44-positive cell types include epithelial cells, glial cells, fibroblasts and myocytes. This broad distribution suggest a general role in cell-cell and cell-matrix adhesion. CD44 is involved in T cell activation and adhesion. Triggering of CD44 increases homotypic T cell aggregation mediated via LFA-1. CD44 is linked to the cytoskeleton. Furthermore CD44 has an accessory role in lymphocyte adhesion to high endothelial venules. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | HM2127-100UG |
Price | $488 |
Order / More Info | CD44, Human Antibody from HYCULT BIOTECH |
Product Specific References | n/a |