CD59, Human Antibody from HYCULT BIOTECH

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Antigenic SpecificityCD59, Human
CloneMEM-43
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
Formatunconjugated
Size20 µg
Concentrationn/a
ApplicationsFlow cytometry, Functional studies, Immuno precipitation, Western blot. RUO
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DescriptionThe antibody is the prototypic antibody for the CD59 determinant, a PI-linked glycoprotein of 18-25 kDa, which is broadly expressed on most types of cells. The antigen is the major complement-protecting molecule of human cells. It is expressed on all leukocytes, erythrocytes and most other cell types. Binding of this antibody inhibits the complement-protecting activity of CD59. CD59 is one of the complement regulatory membrane proteins that is missing in Paroxysmal Nocturnal Haemoglobinuria (PNH). Anti CD59 reagents may be useful in the differential diagnosis of PNH type II and PNH type I. Recently a role for CD59 in LPS signal transduction has been reported in keratinocytes. The antibody reacts with well defined epitope (W40, R-53) on CD59 molecule.
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #HM2120-20UG
Price$157
Order / More InfoCD59, Human Antibody from HYCULT BIOTECH
Product Specific Referencesn/a
HYCULT BIOTECH
HYCULT BIOTECH
HYCULT BIOTECH
Frontstraat 2a
5405 PB Uden THE NETHERLANDS
P: +31 (0)413 251335
F: +31 (0)413 248353

info@hycultbiotech.com

https://www.hycultbiotech.com

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