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Antigenic Specificity | Mouse CTLA-4 |
Clone | UC10-4F10-11 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG1 kappa |
Format | Protein A/G purified, low endotoxin |
Size | 50mg |
Concentration | ≥ 2.0 mg/ml |
Applications | Flow Cytometry, Western Blot, Functional Assays, Immunoprecipitation. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (UC10-4F10-11) recognizes an epitope on Mouse CD152. CD152, also known as CTLA-4 or Ly-56 has significant similarity to CD28 in amino acid sequence, structure, and genomic organization. Furthermore, CD152 and CD28 share common B7 family counter-receptors. Unlike CD28, CD152 expression appears to be restricted to activated T cells and CD25+CD4+ regulatory T (Treg) cells. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation. |
Immunogen | Purified Recombinant Mouse CTLA4 Fc Fusion Protein |
Other Names | Ctla4, Cytotoxic T-lymphocyte protein 4, CD152 |
Gene, Accession # | UniProt: P09793 |
Catalog # | ICH1085-50mg |
Price | $1775 |
Order / More Info | Mouse CTLA-4 Antibody from ICHORBIO |
Product Specific References | n/a |
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