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Antigenic Specificity | PCSK9 (Alirocumab biosimilar) |
Clone | monoclonal |
Host Species | Humanized |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A/G purified, low endotoxin |
Size | 100mg |
Concentration | 1.0 - 5.0 mg/ml |
Applications | RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: detects human PCSK9. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Alirocumab. Alirocumab biosimilar is a human monoclonal antibody (IgG1 isotype) that targets proprotein convertase subtilisin kexin type 9 (PCSK9), is a PCSK9 inhibitor produced by recombinant DNA technology in Chinese Hamster Ovary cell suspension culture. Alirocumab biosimilar consists of two disulfide-linked human heavy chains, each covalently linked through a disulfide bond to a human kappa light chain. A single Nlinked glycosylation site is located in each heavy chain within the CH2 domain of the Fc constant region of the molecule. The variable domains of the heavy and light chains combine to form the PCSK9 binding site within the antibody. Alirocumab biosimilar has an approximate molecular weight of 146 kDa. |
Immunogen | n/a |
Other Names | Proprotein convertase subtilisin/kexin type 9, NARC-1, PC9 |
Gene, Accession # | UniProt: Q8NBP7 |
Catalog # | ICH4016-100mg |
Price | $5000 |
Order / More Info | PCSK9 (Alirocumab biosimilar) Antibody from ICHORBIO |
Product Specific References | n/a |
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