Mouse CD134 Antibody from ICHORBIO
Search, find, compare suppliers for anti-Mouse CD134 antibody, protein, ELISA kits.
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| Antigenic Specificity | Mouse CD134 |
| Clone | OX-86 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | Protein A/G purified, low endotoxin |
| Size | 100mg |
| Concentration | ≥ 2.0 mg/ml |
| Applications | Activation, Flow Cytometry, Immunohistochemistry, Western Blotting. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Clone OX-86 reacts with murine CD134 (OX-40, TNFRSF4). CD134 functions as an important immune checkpoint, and its depletion in murine mouse models demonstrate that lack of CD134 expression leads to reduced CD4+ and CD8+ T cells. When CD134 is bound by its corresponding ligand (OX-40L), an optimal T cell response is generated and plays a significant role in determining the amount of memory T-cells remaining after the immune response. CD134 has also been found to play an important role in carcinogenesis, as treatment with activating in vivo antibodies against CD134 enhanced tumor growth, suggesting that CD134 is an important tumor suppressor, and its absence disrupts the immune response to tumors |
| Immunogen | n/a |
| Other Names | OX-40, TNFRSF4, ACT35 |
| Gene, Accession # | n/a |
| Catalog # | ICH1196-100mg |
| Price | $2600 |
| Order / More Info | Mouse CD134 Antibody from ICHORBIO |
| Product Specific References | n/a |
ICHORBIO
ICHORBIO
Boston House, Grove Business Park
Downsview Road
Wantage OX12 9FF ENGLAND
orders@ichor.bio
https://ichor.bio
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987 Old Eagle School Rd, Ste 709
Wayne, PA 19087
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Profile of ICHORBIO