CD28 (Theralizumab biosimilar) Antibody from ICHORBIO

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Antigenic SpecificityCD28 (Theralizumab biosimilar)
Clonemonoclonal
Host Speciesn/a
Reactive Specieshuman
IsotypeIgG4
FormatProtein A/G purified, low endotoxin
Size1mg
Concentration5mg/ml
ApplicationsFunctional Assays. RUO
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DescriptionSpecificity: detects human CD28. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Theralizumab. Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune system's T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner in the reaction through one of its ligands (B7 family). It was withdrawn from development after inducing severe inflammatory reactions as well as chronic organ failure in the first-in-human study by PAREXEL in London in March 2006.
Immunogenn/a
Other NamesTGN1412, CD28-SuperMAB, TAB08
Gene, Accession #UniProt: P10747
Catalog #ICH5023-1mg
Price$300
Order / More InfoCD28 (Theralizumab biosimilar) Antibody from ICHORBIO
Product Specific Referencesn/a
ICHORBIO
ICHORBIO
ICHORBIO
Boston House, Grove Business Park
Downsview Road
Wantage OX12 9FF ENGLAND

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Wayne, PA 19087
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