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Antigenic Specificity | Human CD68 |
Clone | KP1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein A/G purified, low endotoxin |
Size | 100mg |
Concentration | ≥ 2.0 mg/ml |
Applications | Blotting, Dot Blot, Electron Microscopy, Flow Cytrometry, Immunocytochemistry, ICFC, Immunohistochemistry, IHC-paraffin, Immunoprecipitation, Western Blotting. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-CD68 antibody (clone KP1) activity is directed against human CD68. KP1 was originally used as a pan-monocytic/macrophage marker against CD68; however, CD68 is not a macrophage specific antigen and KP1 is known to stain neutrophils and other non-macrophage-like cells. KP1 reacts against CD68 in a wide range of healthy and disease-associated (rheumatoid arthritis and osteoarthritis)5 tissues as well as a variety of neoplasms, tumor cell lines, and tumor-associated macrophages. KP1 detects a fixation-resistant epitope that is likely glycan-based which is shared by many cell types.KP1 was developed by immunizing Balb/c mice against a lysosomal fraction of human lung. Hybridoma supernatants derived from spleen cells were screened on cryostat human lung and tonsil sections as well as paraffin wax sections of lung tissue fixed in formol saline. |
Immunogen | Lysosomal fraction of human lung |
Other Names | GP110, LAMP4, SCARD1 |
Gene, Accession # | n/a |
Catalog # | ICH1190-100mg |
Price | $2600 |
Order / More Info | Human CD68 Antibody from ICHORBIO |
Product Specific References | PD-1 Blockade Restores the Proliferation of Peripheral Blood Lymphocyte and Inhibits Lymphocyte Apoptosis in a BALB/c Mouse Model of CP BVDV Acute Infection: https://www.frontiersin.org/articles/10.3389/fimmu.2021.727254/full |
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