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Antigenic Specificity | 4-1BB (Utomilumab biosimilar) |
Clone | monoclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | IgG2-lambda 2 |
Format | Protein A/G purified, low endotoxin |
Size | 50mg |
Concentration | 5mg/ml |
Applications | Functional Assays. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: detects human CD137. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Utomilumab. RUO Utomilumab is a fully-human IgG2 agonist mAb that selectively binds human 4-1BB/CD137, resulting in NF-κB activation and downstream cytokine production in cell lines and primary lymphocytes. Utomilumab can induce human leukocyte proliferation and has demonstrated significant antitumor activity as a single agent in human peripheral blood lymphocyte (PBL) SCID xenograft tumor models. |
Immunogen | n/a |
Other Names | 4-1BB ligand receptor, T-cell antigen 4-1BB, Tnfrsf9, Ila, Ly63, CD137 |
Gene, Accession # | UniProt: Q07011 |
Catalog # | ICH5014-50mg |
Price | $3750 |
Order / More Info | 4-1BB (Utomilumab biosimilar) Antibody from ICHORBIO |
Product Specific References | n/a |
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