Mouse CD105 Antibody from ICHORBIO
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| Antigenic Specificity | Mouse CD105 |
| Clone | MJ7/18 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a kappa |
| Format | Protein A/G purified, low endotoxin |
| Size | 100mg |
| Concentration | ≥ 2.0 mg/ml |
| Applications | Agonist, Cell Separation, ELISA, Flow Cytometry, Immunofluorescence, IF Microscopy, Immunohistochemistry,IHC FF, Immunoprecipitation, LCI, Western Blot. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MJ7/18 activity is directed against mouse CD105 (endoglin). CD105 (endoglin) is a TGF-β superfamily co-receptor that promotes angiogenesis, is involved in endothelial integrin-mediated mural cell and leukocyte adhesion, antagonizes TGF-β mediated ERK activation, is essential to the immune response of macrophages, regulates trophoblast differentiation and invasion during pregnancy, promotes T-cell proliferation, and regulates differentiation and collagen expression in myofibroblasts |
| Immunogen | MJ7/18 was produced by immunizing rats with inflamed mouse skin and selecting for reactivity with endothelial cells. MJ7/18 predominantly stains vascular endothelial cells and is a marker of mouse endothelium |
| Other Names | Endoglin, Ancillary TGF-beta Receptor |
| Gene, Accession # | n/a |
| Catalog # | ICH1191-100mg |
| Price | $2600 |
| Order / More Info | Mouse CD105 Antibody from ICHORBIO |
| Product Specific References | PD-1 Blockade Restores the Proliferation of Peripheral Blood Lymphocyte and Inhibits Lymphocyte Apoptosis in a BALB/c Mouse Model of CP BVDV Acute Infection: https://www.frontiersin.org/articles/10.3389/fimmu.2021.727254/full |
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