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Antigenic Specificity | Mouse CD115 |
Clone | AFS98 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a kappa |
Format | Protein A/G purified, low endotoxin |
Size | 50mg |
Concentration | 1.0 - 5.0 mg/ml |
Applications | Western Blot, Blocking, Functional Assays, Flow Cytometry. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98) recognizes an epitope on Mouse M-CSFR. Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion. |
Immunogen | Purified Recombinant Mouse M-CSFR |
Other Names | Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, Csf1r, Csfmr, Fms |
Gene, Accession # | UniProt: P09581 |
Catalog # | ICH1068UL-50mg |
Price | $2300 |
Order / More Info | Mouse CD115 Antibody from ICHORBIO |
Product Specific References | n/a |
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