Human CD119 Antibody from ICHORBIO
Search, find, compare suppliers for anti-Human CD119 antibody, protein, ELISA kits.
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| Antigenic Specificity | Human CD119 |
| Clone | GIR 208 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein A/G purified, low endotoxin |
| Size | 25mg |
| Concentration | 1.0 - 5.0 mg/ml |
| Applications | Immunoprecipitation, Western Blot, ELISA, Neutralization, Flow Cytometry. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208) recognizes Human IFN gamma R alpha. Interferon-gamma (IFN-gamma) exerts its biologic effects by interacting with a single high affinity receptor, IFN-gamma receptor. This receptor is present on almost all cell types except mature erythrocytes. The IFN-gamma receptor consists of two polypeptide chains alpha and beta and requires association of JAK1, JAK2 and Stat1 for IFN-gamma signal transduction. In signal transduction, IFN-gamma induces tyrosine phosphorylation of IFN-gamma receptor alpha (IFNGR1) leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-gamma induced gene transcription. The IFN-gamma receptor is structurally related to the recently cloned IL-10 receptor. GIR 208 binds IFNGR1 and blocks binding of IFN-gamma to the receptor. |
| Immunogen | Human IFN-gamma R alpha, Purified from human placenta |
| Other Names | Interferon gamma receptor 1, IFN-gamma receptor 1, IFN-gamma-R1, CDw119, Interferon gamma receptor alpha-chain2, IFN-gamma-R-alpha |
| Gene, Accession # | UniProt: P15260 |
| Catalog # | ICH1028-25mg |
| Price | $1100 |
| Order / More Info | Human CD119 Antibody from ICHORBIO |
| Product Specific References | n/a |
ICHORBIO
ICHORBIO
Boston House, Grove Business Park
Downsview Road
Wantage OX12 9FF ENGLAND
orders@ichor.bio
https://ichor.bio
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987 Old Eagle School Rd, Ste 709
Wayne, PA 19087
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