PCSK9 (Alirocumab biosimilar) Antibody from ICHORBIO

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Antigenic SpecificityPCSK9 (Alirocumab biosimilar)
Clonemonoclonal
Host SpeciesHumanized
Reactive Specieshuman
IsotypeIgG1
FormatProtein A/G purified, low endotoxin
Size10mg
Concentration1.0 - 5.0 mg/ml
ApplicationsRUO
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DescriptionSpecificity: detects human PCSK9. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Alirocumab. Alirocumab biosimilar is a human monoclonal antibody (IgG1 isotype) that targets proprotein convertase subtilisin kexin type 9 (PCSK9), is a PCSK9 inhibitor produced by recombinant DNA technology in Chinese Hamster Ovary cell suspension culture. Alirocumab biosimilar consists of two disulfide-linked human heavy chains, each covalently linked through a disulfide bond to a human kappa light chain. A single Nlinked glycosylation site is located in each heavy chain within the CH2 domain of the Fc constant region of the molecule. The variable domains of the heavy and light chains combine to form the PCSK9 binding site within the antibody. Alirocumab biosimilar has an approximate molecular weight of 146 kDa.
Immunogenn/a
Other NamesProprotein convertase subtilisin/kexin type 9, NARC-1, PC9
Gene, Accession #UniProt: Q8NBP7
Catalog #ICH4016-10mg
Price$1145
Order / More InfoPCSK9 (Alirocumab biosimilar) Antibody from ICHORBIO
Product Specific Referencesn/a
ICHORBIO
ICHORBIO
ICHORBIO
Boston House, Grove Business Park
Downsview Road
Wantage OX12 9FF ENGLAND

orders@ichor.bio

https://ichor.bio

U.S. OFFICE
987 Old Eagle School Rd, Ste 709
Wayne, PA 19087
us@ichor.bio


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