Edit |   |
---|---|
Antigenic Specificity | Human CD8 |
Clone | UCHT-4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | Protein A/G purified, low endotoxin |
Size | 50mg |
Concentration | 1.0 - 5.0 mg/ml |
Applications | Flow Cytometry, Western Blot, Immunoprecipitation, Functional Assays, IHC, Immunofluorescence, ELISA. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-CD8 In Vivo Antibody - Low Endotoxin (UCHT-4) recognizes Human CD8. Anti-Human CD8 recognizes a T-cell glycoprotein cell surface complex (Mr 32 kDa) which defines the cytotoxic/suppressor population of mature T-lymphocytes. The CD8 complex interacts with class I MHC molecules resulting in increased adhesion between CD8+ T-lymphocytes and their target cells. Binding of the CD8 antigen to Class I MHC molecules enhances T-cell activation. The cytoplasmic portion of the CD8 antigen is associated with a protein tyrosine kinase (p56lck). Anti-CD8 may be used in studies of immunoregulation and T-lymphocyte mediated suppression, autoimmune disorders, immunodeficiency states and acute lymphoblastic leukemia and lymphoma. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | ICH1005-50mg |
Price | $1775 |
Order / More Info | Human CD8 Antibody from ICHORBIO |
Product Specific References | n/a |
U.S. OFFICE
987 Old Eagle School Rd, Ste 709
Wayne, PA 19087
us@ichor.bio