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Antigenic Specificity | CD52 (Alemtuzumab biosimilar) |
Clone | monoclonal |
Host Species | Humanized |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein A/G purified, low endotoxin |
Size | 10mg |
Concentration | 1.0 - 5.0 mg/ml |
Applications | RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: detects human CD52. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Alemtuzumab. Alemtuzumab biosimilar is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) directed against the 21-28 kD cell surface glycoprotein, CD52, is an IgG1 kappa antibody with human variable framework and constant regions, and complementarity-determining regions from a murine (rat) monoclonal antibody. The alemtuzumab biosimilar has an approximate molecular weight of 150 kD and is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium. |
Immunogen | n/a |
Other Names | Campath-1 antigen, Cambridge pathology 1 antigen, HE5 |
Gene, Accession # | UniProt: P31358 |
Catalog # | ICH4002-10mg |
Price | $1145 |
Order / More Info | CD52 (Alemtuzumab biosimilar) Antibody from ICHORBIO |
Product Specific References | Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression: https://www.nature.com/articles/s41587-022-01540-7 |
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