Mouse IL-1R Antibody from ICHORBIO
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| Antigenic Specificity | Mouse IL-1R |
| Clone | JAMA-147 |
| Host Species | Armenian Hamster |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | Protein A/G purified, low endotoxin |
| Size | 5mg |
| Concentration | 1.0 - 5.0 mg/ml |
| Applications | Immunoprecipitation, Western Blot, Blocking, Flow Cytometry. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Anti-IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) recognizes Mouse IL-1 R1. IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1alpha and IL-1beta exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1alpha and IL-1beta, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein. |
| Immunogen | Extracellular domain of mouse IL-1 R type 1 |
| Other Names | Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha,IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a |
| Gene, Accession # | UniProt: P13504 |
| Catalog # | ICH1117-5mg |
| Price | $375 |
| Order / More Info | Mouse IL-1R Antibody from ICHORBIO |
| Product Specific References | n/a |
ICHORBIO
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