Mouse TNF Receptor I Antibody from ICHORBIO
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| Antigenic Specificity | Mouse TNF Receptor I |
| Clone | 55R-593 |
| Host Species | Armenian Hamster |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | Protein A/G purified, low endotoxin |
| Size | 5mg |
| Concentration | 1.0 mg/ml |
| Applications | Immunoprecipitation, Western Blot. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Armenian Hamster anti-Mouse CD120A (Clone 55R-593) recognizes Mouse CD120A. Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-A and TNF-B (also known as LT-A). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-κB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding. |
| Immunogen | E. coli-expressed extracellular domain of the mouse TNFRI protein |
| Other Names | Tumor necrosis factor receptor superfamily member 1A, Tnfrsf1a, TNF-R1, TNF-RI, p55, p60, CD120a |
| Gene, Accession # | UniProt: P25118 |
| Catalog # | ICH1069-5mg |
| Price | $375 |
| Order / More Info | Mouse TNF Receptor I Antibody from ICHORBIO |
| Product Specific References | n/a |
ICHORBIO
ICHORBIO
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