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Antigenic Specificity | Human CD25 |
Clone | 7G7B6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | Protein A/G purified, low endotoxin |
Size | 100mg |
Concentration | 1.0 - 5.0 mg/ml |
Applications | ELISA, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Clone 7G7B6 reacts with human CD25. CD25 (IL-2Rα) is the 55 kDa subunit of the interleukin 2 receptor alpha chain which has been shown to play roles in lymphocyte differentiation, activation, and proliferation. IL-2Rα is a transmembrane glycoprotein comprised of a heavily glycosylated extracellular domain, a transmembrane region and a short cytoplasmic tail. IL-2Rα heterodimerizes with IL-2Rβ (CD122) and IL-2Rγ (CD132) and forms the IL-2 receptor complex. IL-2Rα by itself binds IL-2 with relatively low affinity, while the IL-2 receptor complex binds IL-2 with high affinity. IL-2Rα mutations cause severe immunodeficiency. |
Immunogen | Recombinant human peripheral blood mononuclear cells (PBMCs) |
Other Names | IL2RA, Interleukin-2 receptor subunit alpha, TAC, p60 |
Gene, Accession # | UniProt: P01589 |
Catalog # | ICH1163UL-100mg |
Price | $3200 |
Order / More Info | Human CD25 Antibody from ICHORBIO |
Product Specific References | n/a |
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