Mouse CXCR3 Antibody from ICHORBIO
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| Antigenic Specificity | Mouse CXCR3 |
| Clone | CXCR3-173 |
| Host Species | Armenian Hamster |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | Protein A/G purified, low endotoxin |
| Size | 25mg |
| Concentration | ≥ 2.0 mg/ml |
| Applications | Flow Cytometry, Neutralization. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CXCR3-173 activity is directed against murine CD183 (CXCR3). Hamsters were tested by ELISA for seropositivity against CXCR3 peptide and hybridomas were generated, screened by FACS, purified, and tested for: staining, CXCR3 blockade in vitro, and endotoxin levels. CXCR3-173 detects the native form of CXCR3, and therefore does not work in Western blotting.CXCR3-173 has potential use in immunotherapeutic approaches to inhibit transplant rejection and immune related diseases. In vitro, CXCR3-173 blocks chemotaxis in response to CXCL10 or CXCL11 but not CXCL9. In vivo, CXCR3-173 prolongs both cardiac and islet allograft survival in a manner further enhanced by rapamycin. |
| Immunogen | CXCR3-173 was generated by immunizing Armenian hamsters with a peptide sequence unique to mouse CXCR3 which encompasses amino acids 1-37. |
| Other Names | CXCR3G, protein-coupled receptor 9 (GPR9), CKR-L2, IP10 receptor (IP10-R), Mig receptor (Mig-R ), CD183 |
| Gene, Accession # | n/a |
| Catalog # | ICH1201-25mg |
| Price | $1100 |
| Order / More Info | Mouse CXCR3 Antibody from ICHORBIO |
| Product Specific References | n/a |
ICHORBIO
ICHORBIO
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Wantage OX12 9FF ENGLAND
orders@ichor.bio
https://ichor.bio
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987 Old Eagle School Rd, Ste 709
Wayne, PA 19087
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