Mouse CTLA-4 Antibody from ICHORBIO

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Antigenic SpecificityMouse CTLA-4
Clone9H10
Host SpeciesSyrian Hamster
Reactive Speciesmouse
IsotypeIgG
FormatProtein A/G purified, low endotoxin
Size5mg
Concentration1.0 - 5.0 mg/ml
ApplicationsWestern Blot, Blocking, ELISA, Flow Cytometry. RUO
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DescriptionSpecificity: Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4. CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) also known as CD152, is a protein which is expressed on the surface of Helper T cells and plays an important regulatory role in the immune system. CTLA4 is a member of the immunoglobulin superfamily, expressed on the surface of Helper T cells. CTLA4 transmits an inhibitory signal to T cells. CTLA4 is potentially therapeutic in auto-immune diseases4, such as rheumatoid arthritis, HIV, autoimmune thyroid disease, multiple sclerosis and may also be useful during organ transplantation and cancer treatment. Clone 9H10 antibody has been shown to promote T cell co-stimulation by blocking CTLA4 binding, allowing for CD28 binding.
ImmunogenMouse CTLA-4-human IgG1 fusion protein
Other NamesCtla4, Cytotoxic T-lymphocyte protein 4, CD152
Gene, Accession #UniProt: P09793
Catalog #ICH1084UL-5mg
Price$470
Order / More InfoMouse CTLA-4 Antibody from ICHORBIO
Product Specific Referencesn/a
ICHORBIO
ICHORBIO
ICHORBIO
Boston House, Grove Business Park
Downsview Road
Wantage OX12 9FF ENGLAND

orders@ichor.bio

https://ichor.bio

U.S. OFFICE
987 Old Eagle School Rd, Ste 709
Wayne, PA 19087
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