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Antigenic Specificity | CD3e + CD20 (Mosunetuzumab biosimilar) |
Clone | monoclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A/G purified, low endotoxin |
Size | 10mg |
Concentration | 5mg/ml |
Applications | Functional Assays. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: detects human CD3/CD20. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Mosunetuzumab. ichorbio's Mosunetuzumab biosimilar is a bispecific, humanized monoclonal antibody with potential antineoplastic activity. Anti-CD20/CD3 bispecific monoclonal antibody BTCT4465A contains two antigen-recognition sites: one for human CD3, a T-cell surface antigen, and one for human CD20, a tumor-associated antigen (TAA) that is exclusively expressed on B cells during most stages of B-cell development and is often overexpressed in B-cell malignancies. Upon administration, BTCT4465A binds to both T cells and CD20-expressing tumor B cells; this cross-links T cells to tumor cells, and may result in a potent cytotoxic T-lymphocyte (CTL) response against CD20-expressing tumor B cells. |
Immunogen | n/a |
Other Names | BTCT4465A |
Gene, Accession # | UniProt: P07766, P11836 |
Catalog # | ICH5026-10mg |
Price | $2200 |
Order / More Info | CD3e + CD20 (Mosunetuzumab biosimilar) Antibody from ICHORBIO |
Product Specific References | n/a |
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