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Antigenic Specificity | Mouse IL2RA |
Clone | PC61 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 lambda |
Format | Protein A/G purified, low endotoxin |
Size | 5mg |
Concentration | ≥ 2.0 mg/ml |
Applications | Immunoprecipitation, Western Blot, Functional Assays, Blocking, Flow Cytometry, IHC (Frozen). RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-CD25 In Vivo Antibody - Ultra Low Endotoxin (PC61) recognizes an epitope on Mouse IL-2 RA. IL-2 receptor alpha chain (IL-2Ralpha) is a component of high-affinity IL-2 receptors and thus is a key regulator of lymphocyte proliferation. IL-2R alpha expression occurs at specific stages of early T and B lymphocyte development and is induced upon activation of mature lymphocytes. IL-2R alpha is essential for regulation of both the size and content of the peripheral lymphoid compartment, probably by influencing the balance between clonal expansion and cell death following lymphocyte activation. IL-2Ralpha is also important in the formation of high-affinity binding sites, and the inducibility of the alpha gene contributes to the highly regulated and transient display of high-affinity IL-2R. |
Immunogen | IL-2-dependent cytolytic mouse T-cell clone B6.1 |
Other Names | Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, Il2ra, p55, CD25 |
Gene, Accession # | UniProt: P01590 |
Catalog # | ICH1054UL-5mg |
Price | $470 |
Order / More Info | Mouse IL2RA Antibody from ICHORBIO |
Product Specific References | n/a |
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