Mouse TCR beta Antibody from ICHORBIO
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| Antigenic Specificity | Mouse TCR beta |
| Clone | H57-597 |
| Host Species | Armenian Hamster |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | Protein A/G purified, low endotoxin |
| Size | 25mg |
| Concentration | ≥ 5.0 mg/ml |
| Applications | Flow Cytometry, Costimulatory, Depletion, Immunoprecipitation, IHC (Frozen), IHC (Paraffin), CODEX. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Clone H57-597 recognizes an epitope on the constant region of mouse TCRβ. Clone H57-597 does not cross-react with γδ T cells. TCRβ antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRβ), expressed on αβ thymocytes and T lymphocytes, as well as natural killer T (NKT) cells. TCRβ is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRα) via a disulfide bond. TCRα/β does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling. TCRα/β recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival. |
| Immunogen | Affinity purified TCR from mouse DO-11.10 cells |
| Other Names | TCR-β chain, TCR-β, β-TCR |
| Gene, Accession # | n/a |
| Catalog # | ICH1153-25mg |
| Price | $1100 |
| Order / More Info | Mouse TCR beta Antibody from ICHORBIO |
| Product Specific References | n/a |
ICHORBIO
ICHORBIO
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Wantage OX12 9FF ENGLAND
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Wayne, PA 19087
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