CD14 (Atibuclimab biosimilar) Antibody from ICHORBIO
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| Antigenic Specificity | CD14 (Atibuclimab biosimilar) |
| Clone | monoclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | IgG4 |
| Format | Protein A/G purified, low endotoxin |
| Size | 100mg |
| Concentration | 5mg/ml |
| Applications | Functional Assays. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: detects human CD14. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Atibuclimab. RUO atibuclimab is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis. It acts as a pattern recognition receptor for bacterial cell wall components in gram-positive and negative bacteria. CD14 antibody action stimulates a pro-inflammatory cytokine cascade often associated with inflammation in sepsis. Atibuclimab neutralization of this antibody results in the inhibition of TNF-a, IL-6 and IL-10, dampening systemic inflammatory responses. Atibuclimab also delays the release of sTNFR(1) and IL-1ra. |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | UniProt: P08571 |
| Catalog # | ICH5016-100mg |
| Price | $5000 |
| Order / More Info | CD14 (Atibuclimab biosimilar) Antibody from ICHORBIO |
| Product Specific References | n/a |
ICHORBIO
ICHORBIO
Boston House, Grove Business Park
Downsview Road
Wantage OX12 9FF ENGLAND
orders@ichor.bio
https://ichor.bio
U.S. OFFICE
987 Old Eagle School Rd, Ste 709
Wayne, PA 19087
us@ichor.bio
Profile of ICHORBIO