Edit |   |
---|---|
Antigenic Specificity | Mouse Ly49C |
Clone | 4LO3311 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG3 kappa |
Format | Protein A/G purified, low endotoxin |
Size | 50mg |
Concentration | ≥ 2.0 mg/ml |
Applications | Depletion, Flow Cytometry, Immunoprecipitation. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: 4LO3311 activity is directed against Ly49C (Killer cell lectin-like receptor 3, KLRA3; NK2.1). 4LO3311 binds an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain. 4LO3311 recognizes an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain. 4LO3311 recognizes Ly-49CBALB but not Ly-49AB6, Ly-49ABALB, BBALB, DB6, EB6, FB6, GB6, GBALB, or H. 4LO3311 plus complement inhibits NK cell and antibody-dependent cellular cytotoxicity (ADCC) activity in C3H spleen cells4. 4LO3311 inhibits C57BL/6 and C3H NK cell activity but has no effect on NZB NK cells. |
Immunogen | 4LO3311 was generated by immunizing 129/SvJ mice with C57BL/6 NK-enriched spleen cells |
Other Names | Ly-49 inhibitory receptors C |
Gene, Accession # | n/a |
Catalog # | ICH1202-50mg |
Price | $1775 |
Order / More Info | Mouse Ly49C Antibody from ICHORBIO |
Product Specific References | n/a |
U.S. OFFICE
987 Old Eagle School Rd, Ste 709
Wayne, PA 19087
us@ichor.bio