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Antigenic Specificity | Mouse IFN beta |
Clone | MIB-5E9.1 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | Protein A/G purified, low endotoxin |
Size | 50mg |
Concentration | 1.0 mg/ml |
Applications | Western Blot, Blocking. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) recognizes Mouse IFN beta. Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-alpha proteins and a single IFN-beta protein. The second class, type II IFN, consists of a single protein, IFN-gamma. IFN-alpha and IFN-beta signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN-beta has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-beta's therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines. |
Immunogen | n/a |
Other Names | IFN-b, IFN-beta, Type-1 interferon, Interferon beta |
Gene, Accession # | UniProt: P01575 |
Catalog # | ICH1124-50mg |
Price | $1775 |
Order / More Info | Mouse IFN beta Antibody from ICHORBIO |
Product Specific References | n/a |
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