Integrin Beta 3 (GPIIIa, CD61), PSI Domain Antibody from KERAFAST, INC.

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Antigenic SpecificityIntegrin Beta 3 (GPIIIa, CD61), PSI Domain
CloneAP3
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size100ug
Concentrationn/a
ApplicationsFlow Cytometry (0.02 mg/mL), ELISA capture (10ug/mL) and detection (10ug/mL)
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DescriptionAnti-Integrin Beta 3 (GPIIIa, CD61), PSI Domain [AP-3] Antibody. Target: Glycoprotein IIIa. Epitope: PSI/Hybrid (amino acids 50-62)
ImmunogenHuman platelet
Other Namesn/a
Gene, Accession #Accession: P05106
Catalog #EBW106
Price$360
Order / More InfoIntegrin Beta 3 (GPIIIa, CD61), PSI Domain Antibody from KERAFAST, INC.
Product Specific References
  1. Pidard D, Montgomery RR, Bennett JS, Kunicki TJ. Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets. J Biol Chem. 1983 Oct 25;258(20):12582-6.
  2. Peterson JA, Nelson TN, Kanack AJ, Aster RH. Fine specificity of drug-dependent antibodies reactive with a restricted domain of platelet GPIIIA. Blood. 2008 Feb 1;111(3):1234-9. Epub 2007 Oct 24.
  3. Ruiz C, Liu CY, Sun QH, Sigaud-Fiks M, Fressinaud E, Muller JY, Nurden P, Nurden AT, Newman PJ, Valentin N. A point mutation in the cysteine-rich domain of glycoprotein (GP) IIIa results in the expression of a GPIIb-IIIa (alphaIIbbeta3) integrin receptor locked in a high-affinity state and a Glanzmann thrombasthenia-like phenotype. Blood. 2001 Oct 15;98(8):2432-41.
  4. Honda S, Tomiyama Y, Pelletier AJ, Annis D, Honda Y, Orchekowski R, Ruggeri Z, Kunicki TJ. Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit. J Biol Chem. 1995 May 19;270(20):11947-54.
  5. Faralli JA, Dimeo KD, Trane RM, Peters D. Absence of a secondary glucocorticoid response in C57BL/6J mice treated with topical dexamethasone. PLoS One. 2018 Mar 2;13(3):e0192665. View Article
  6. Faralli JA, Filla MS, Peters DM. Effect of αvβ3 Integrin Expression and Activity on Intraocular Pressure. Invest Ophthalmol Vis Sci. 2019 Apr 1;60(5):1776-1788. View Article
KERAFAST, INC.
KERAFAST, INC.
KERAFAST, INC.
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