ADAM17 (mouse), Cytoplasmic Domain Antibody from KERAFAST, INC.

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Antigenic SpecificityADAM17 (mouse), Cytoplasmic Domain
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatunconjugated
Size100uL
Concentrationn/a
ApplicationsWB (1:1000)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionAnti-ADAM17 (mouse), Cytoplasmic Domain Antibody. Target: GST-ADAM17 Cytoplasmc Domain. Epitope: Cytoplasmic domain
ImmunogenGST-cyto corresponding to the cytoplasmic domain of mouse ADAM17
Other Namesn/a
Gene, Accession #Accession: P78536
Catalog #EHS008
Price$328
Order / More InfoADAM17 (mouse), Cytoplasmic Domain Antibody from KERAFAST, INC.
Product Specific References
  1. Schlondorff, J.; Becherer, J. D.; Blobel, C. P. Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE). Biochem J. 2000, 347, 131-138.
  2. Zheng, Y.; Schlondorff, J.; Blobel, C. P. Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1. J. Biol. Chem. 2002, 277, 42463-42470.
  3. Horiuchi, K.; Kimura T.; Miyamoto T.; Takaishi H.; Okada Y.; Toyama, Y., Blobel, C. P. Cutting edge: TNF-alpha-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock. J. Immunol. 2007, 179, 2686-2689.
  4. Le Gall, S. M., Maretzky, T., Issuree, P. D., Niu, X. D.; Reiss, K., Saftig, P., Khokha, R., Lundell, D., Blobel, C. P. ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site. J. Cell. Sci. 2010, 123, 3913-3922.
  5. Maretzky, T., Evers, A., Zhou, W., Swendeman, S. L., Wong, P. M., Rafii, S., Reiss, K., Blobel C. P. Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17. Nat. Commun. 2011, 2, 1-25.
  6. McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK, Berger T,Murthy A, Duncan G, Xu HC, Lang KS, Haussinger D, Wakeham A, Itie-Youten A,Khokha R, Ohashi PS, Blobel CP, Mak TW. iRhom2 regulation of TACE controlsTNF-mediated protection against Listeria and responses to LPS. Science. 2012 Jan 13;335(6065):229-32.
KERAFAST, INC.
KERAFAST, INC.
KERAFAST, INC.
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