GW182/TNRC6A Antibody from KERAFAST, INC.

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Antigenic SpecificityGW182/TNRC6A
Clone4B6
Host SpeciesMouse
Reactive Specieshuman and rabbit
IsotypeIgG1
Formatunconjugated
Size2mL
Concentrationn/a
ApplicationsIF 1:10-1:50, WB Neat-1:10
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionAnti-GW182/TNRC6A [4B6] Antibody. Target: GW182
ImmunogenRecombinant protein
Other Namesn/a
Gene, Accession #Accession: NM_014494
Catalog #EUC010
Price$275
Order / More InfoGW182/TNRC6A Antibody from KERAFAST, INC.
Product Specific References
  1. Jakymiw A, Lian S, Eystathioy T, Li S, Satoh M, Hamel JC, Fritzler MJ, Chan EK. Disruption of GW bodies impairs mammalian RNA interference. Nat Cell Biol. 2005 Dec;7(12):1267-74.
  2. Sen GL, Blau HM. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nat Cell Biol. 2005 Jun;7(6):633-6.
  3. Meister G, Landthaler M, Peters L, Chen PY, Urlaub H, Lührmann R, Tuschl T. Identification of novel argonaute-associated proteins. Curr Biol. 2005 Dec 6;15(23):2149-55.
  4. Moser JJ, Fritzler MJ. Cytoplasmic ribonucleoprotein (RNP) bodies and their relationship to GW/P bodies. Int J Biochem Cell Biol. 2010 Jun;42(6):828-43.
  5. Li S, Wang L, Fu B, Berman MA, Diallo A, Dorf ME. TRIM65 regulates microRNA activity by ubiquitination of TNRC6. Proc Natl Acad Sci U S A. 2014 May 13;111(19):6970-5.
  6. Eystathioy T, Chan EK, Tenenbaum SA, Keene JD, Griffith K, Fritzler MJ. A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles. Mol Biol Cell. 2002 Apr;13(4):1338-51.
  7. Eystathioy T, Chan EK, Mahler M, Luft LM, Fritzler ML, Fritzler MJ. A pA binding protein GW182. Hybrid Hybridomics. 2003 Apr;22(2):79-86.

  8. Sharma NR, Majerciak V, Kruhlak MJ, et al. KSHV RNA-binding protein ORF57 inhibits P-body formation to promote viral multiplication by interaction with Ago2 and GW182. Nucleic Acids Res. 2019;47(17):9368-9385. View article
KERAFAST, INC.
KERAFAST, INC.
KERAFAST, INC.
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