Mouse Laminin Alpha5 Antibody from KERAFAST, INC.

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Antigenic SpecificityMouse Laminin Alpha5
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat; not human or rabbit or chicken
Isotypen/a
Formatunconjugated
Size100uL
Concentrationn/a
ApplicationsWB 1:1000, IHC 1:800
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionRabbit-Anti-Mouse Laminin Alpha5 [1586] Antibody. Target: Laminin Α5, laminin alpha5, LAMA6. Epitope: Portions of domains LEb + L4b of mouse LAMA5
ImmunogenRecombinant mouse protein made in bacteria
Other Namesn/a
Gene, Accession #Accession: O15230, NP_001074640.2
Catalog #EWL005
Price$328
Order / More InfoMouse Laminin Alpha5 Antibody from KERAFAST, INC.
Product Specific References
  1. Miner JH, Cunningham J, Sanes JR: Roles for laminin in embryogenesis: Exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain. J Cell Biol 143: 1713-1723, 1998.
  2. Miner JH, Li C: Defective glomerulogenesis in the absence of laminin a5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol 217: 278-289, 2000.
  3. Miner JH, Patton BL, Lentz SI, Gilbert DJ, Snider WD, Jenkins NA, Copeland NG, Sanes JR: The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform. J Cell Biol 137: 685-701, 1997.
  4. Shannon MB, Patton BL, Harvey SJ, Miner JH: A hypomorphic mutation in the mouse Laminin alpha5 gene (Lama5) causes polycystic kidney disease. J Am Soc Nephrol 17: 1913-1922, 2006.
  5. Kikkawa Y, Miner JH: Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function. Dev Biol 296: 265-277, 2006.
  6. Kikkawa Y, Moulson CL, Virtanen I, Miner JH: Identification of the binding site for the Lutheran blood group glycoprotein on laminin alpha 5 through expression of chimeric laminin chains in vivo. J Biol Chem 277: 44864-44869, 2002.
  7. Kikkawa Y, Virtanen I, Miner JH: Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane. J Cell Biol 161: 187-196, 2003.
  8. Moulson CL, Li C, Miner JH: Localization of Lutheran, a novel laminin receptor, in normal, knockout, and transgenic mice suggests an interaction with laminin alpha5 in vivo. Dev Dyn 222: 101-114, 2001.
  9. Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P: Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol 260: 376-390, 2003.
  10. Nguyen NM, Kelley DG, Schlueter JA, Meyer MJ, Senior RM, Miner JH: Epithelial laminin alpha5 is necessary for distal epithelial cell maturation, VEGF production, and alveolization in the developing murine lung. Dev Biol 282: 111-125, 2005.
  11. Nguyen NM, Miner JH, Pierce RA, Senior RM: Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol 246: 231-244, 2002.
  12. St. John PL, Abrahamson DR: Glomerular endothelial cells and podocytes jointly synthesize laminin-1 and -11 chains. Kidney Int 60: 1037-1046, 2001.
  13. St. John PL, Wang R, Yin Y, Miner JH, Robert B, Abrahamson DR: Glomerular laminin isoform transitions: errors in metanephric culture are corrected by grafting. Am J Physiol Renal Physiol 280: F695-705, 2001.
  14. Pierce RA, Griffin GL, Mudd MS, Moxley MA, Longmore WJ, Sanes JR, Miner JH, Senior RM: Expression of laminin alpha3, alpha4, and alpha5 chains by alveolar epithelial cells and fibroblasts. Am J Respir Cell Mol Biol 19: 237-244, 1998.
  15. Meehan DT, Delimont D, Dufek B, Zallocchi M, Phillips G, Gratton MA, Cosgrove D: Endothelin-1 mediated induction of extracellular matrix genes in strial marginal cells underlies strial pathology in Alport mice. Hear Res 341: 100-108, 2016.
  16. Imanishi H, Tsuruta D, Tateishi C, Sugawara K, Kobayashi H, Ishii M, Kishi K: Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis. Med Mol Morphol 47: 38-42, 2014.
  17. Kim ST, Adair-Kirk TL, Senior RM, Miner JH: Functional Consequences of Cell Type-Restricted Expression of Laminin alpha5 in Mouse Placental Labyrinth and Kidney Glomerular Capillaries. PLoS ONE 7: e41348, 2012.
KERAFAST, INC.
KERAFAST, INC.
KERAFAST, INC.
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