Lamin B Receptor (LBR) Antibody from KERAFAST, INC.

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Antigenic SpecificityLamin B Receptor (LBR)
CloneBBmLBR 12.F8
Host SpeciesMouse
Reactive Specieshuman and mouse
IsotypeIgG2b kappa
Formatsupernatant
Size5mL
Concentrationn/a
ApplicationsWB, IHC, ICC, IF
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionAnti-Lamin B Receptor (LBR) [BBmLBR 12.F8] Antibody. Target: Lamin B Receptor. Epitope: Within amino acids residues 1-211 of mouse LBR
Immunogenn/a
Other Namesn/a
Gene, Accession #Accession: Q14739
Catalog #ESG015
Price$275
Order / More InfoLamin B Receptor (LBR) Antibody from KERAFAST, INC.
Product Specific References
  1. Worman, H.J., J. Yuan, G. Blobel, S. D. Georgatos. 1988. A lamin B receptor in the nuclearenvelope. Proc Natl Acad Sci U S A. 85(22):853-4.
  2. Ye, Q., H. J. Worman. 1994. Primary structure analysis and lamin B and DNA binding ofhuman LBR, an integral protein of the nuclear envelope inner membrane. J Biol Chem.269(15):11306-11.
  3. Ye, Q., H. J Worman. 1996. Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to drosophila hp1. J BiolChem. 271:1465314656.
  4. Tsai, P.L., C. Zhao, E. Turner, C. Schlieker. 2016. The Lamin B receptor is essential forcholesterol synthesis and perturbed by disease-causing mutations. Elife. Jun 23;5. pii:e16011. doi: 10.7554/eLife.16011.
  5. Hoffmann, K., C. K. Dreger, A. L. Olins, D. E. Olins, L. D. Shultz, B. Lucke, H. Karl, R. Kaps, D.Muller, A. Vaya, J. Aznar, R. E. Ware, N. Sotelo Cruz, T. H. Lindner, H. Herrmann, A. Reis, K.Sperling. 2002. Mutations in the gene encoding the lamin B receptor produce an alterednuclear morphology in granulocytes (Pelger-Huet anomaly). Nat Genet. 31(4):410-4.
  6. Waterham, H.R., J. Koster, P. Mooyer, Gv. Gv. Noort , R. I. Kelley, W. R. Wilcox, R. J Wanders,R. C. Hennekam, J. C, Oosterwijk. 2003. Autosomal recessive HEM/Greenberg skeletaldysplasia is caused by 3 beta-hydroxysterol delta 14-reductase deficiency due to mutationsin the lamin B receptor gene. Am J Hum Genet. 72(4):1013-7.
  7. Cohen, T.V., K. D Klarmann, K. Sakchaisri, J. P Cooper, D. Kuhns, M. Anver, P. F. Johnson, S. C.Williams, J. R. Keller, C. L. Stewart. 2008. The lamin B receptor under transcriptional controlof C/EBPepsilon is required for morphological but not functional maturation of neutrophils.Hum Mol Genet. 17(19):2921-33.
KERAFAST, INC.
KERAFAST, INC.
KERAFAST, INC.
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2 Shaker Road, Unit B101
Shirley MA 01464
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