IL1RL1, N-terminal Antibody from LSBio
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| Antigenic Specificity | IL1RL1, N-terminal |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Recognizes an epitope within the N-Terminal region (NT) of mouse ST2, a member of the Toll-interleukin 1 receptor (TIR) superfamily, expressed by mast cells and TH2 helper cells, but not by TH1 effector cells. The majority of TIR superfamily members, which includes the Interleukin-1 receptor (IL-1R1), Toll-like receptors (TLRs) and the cytosolic adaptor proteins MyD88, TIRAP, Trif and TRAM, initiate innate immunity through the ultimate activation of the transcription factor NF-kappaB and are inducers of the inflammatory response. In contrast ST2, which itself is unable to activate NF-kappaB, has been identified as a negative regulator of IL-1R1 and TLR4 signaling by sequestering MyD88 and TIRAP in line with its role as a crucial receptor in TH2-cell mediated responses and. |
| Immunogen | n/a |
| Other Names | IL1RL1, DER4, Growth stimulation-expressed, IL33R, Interleukin-1 receptor-like 1, Interleukin 1 receptor-like 1, ST2, ST2L, ST2V, FIT-1, Protein ST2, ST2 protein, IL-1R4, IL1R4 |
| Gene, Accession # | IL1RL1, Gene ID: 9173 |
| Catalog # | LS-C43164-0.1 |
| Price | $425 |
| Order / More Info | IL1RL1, N-terminal Antibody from LSBio |
| Product Specific References | n/a |
LSBio
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