CLEC7A / Dectin 1 Antibody from LSBio
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| Antigenic Specificity | CLEC7A / Dectin 1 |
| Clone | 2A11 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2b |
| Format | biotin conjugate |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flo |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Recognizes murine beta-glucan receptor, also known as Dectin-1. Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macrophages via the protein tyrosine kinase known as Syk. Inhibits the binding of zymosan to macrophages via the beta-glucan receptor. The low endotoxin version is recommended for functional studies. |
| Immunogen | n/a |
| Other Names | CLEC7A, BGR, CANDF4, CLECSF12, Dectin-1, DC-associated C-type lectin 1, DECTIN1, HDectin-1, Beta-glucan receptor, Lectin-like receptor 1, CD369 |
| Gene, Accession # | CLEC7A, Gene ID: 64581 |
| Catalog # | LS-C188260-0.1 |
| Price | $483 |
| Order / More Info | CLEC7A / Dectin 1 Antibody from LSBio |
| Product Specific References | n/a |
LSBio
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