CIDEA / CIDE-A Antibody from LSBio

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Antigenic SpecificityCIDEA / CIDE-A
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, human
Isotypen/a
FormatProtein G purified
Size50 µg
Concentrationn/a
ApplicationsELISA, IF, IHC, WB
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DescriptionSpecificity: Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.
Immunogenn/a
Other NamesCIDEA, CIDE-A, Cell death activator CIDE-A
Gene, Accession #CIDEA, Gene ID: 1149
Catalog #LS-C498624-50
Price$294
Order / More InfoCIDEA / CIDE-A Antibody from LSBio
Product Specific Referencesn/a
LSBio
LSBio
LSBio
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F: 206-577-4565

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