CD79A / CD79 Alpha, aa202-216 Antibody from LSBio

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Antigenic SpecificityCD79A / CD79 Alpha, aa202-216
CloneIGA/1688R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG
FormatProtein A purified
Size100 µg
Concentrationn/a
ApplicationsFlo, IF, IHC-P, WB
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DescriptionSpecificity: A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.
Immunogenn/a
Other NamesCD79A, CD79a antigen, Ig-alpha, MB-1, MB-1 membrane glycoprotein, Surface IgM-associated protein, MB1
Gene, Accession #CD79A, Gene ID: 973
Catalog #LS-B16269-100
Price$495
Order / More InfoCD79A / CD79 Alpha, aa202-216 Antibody from LSBio
Product Specific Referencesn/a
LSBio
LSBio
LSBio
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