Edit |   |
---|---|
Antigenic Specificity | CD71 / Transferrin Receptor |
Clone | 8D3 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | Protein G purified |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flo, IHC, IHC-Fr |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Recognizes mouse CD71, a 95kD cell surface protein that is otherwise known as transferrin receptor. CD71 is a major iron-binding protein, which plays a key role in the transport of iron into cells that require it. In mice, CD71 is widely expressed on a variety of cells, including Sertoli cells and cells which form the blood brain barrier (BBB) in the central nervous system. Recognizes native, soluble and denatured forms of murine CD71. Binding of the 8D3 antibody to CD71 does not inhibit the proliferation of cell lines tested, and does not interfere with the uptake of iron into cells. The antibody has been used as a BBB transporter vector in mice and is suitable for studying CD71 expression, and iron uptake into different tissues, in the mouse. |
Immunogen | n/a |
Other Names | TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1 |
Gene, Accession # | TFRC, Gene ID: 7037 |
Catalog # | LS-C44905-0.5 |
Price | $645 |
Order / More Info | CD71 / Transferrin Receptor Antibody from LSBio |
Product Specific References | n/a |