Edit |   |
---|---|
Antigenic Specificity | CCN4 / WISP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, human |
Isotype | n/a |
Format | Protein G purified |
Size | 50 µg |
Concentration | n/a |
Applications | ELISA, IF, IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan. |
Immunogen | n/a |
Other Names | WISP1, CCN4, WISP1i, WISP1tc, Wnt-1-induced secreted protein, WISP-1, WISP1c, CCN family member 4 |
Gene, Accession # | WISP1, Gene ID: 8840 |
Catalog # | LS-C500015-50 |
Price | $294 |
Order / More Info | CCN4 / WISP1 Antibody from LSBio |
Product Specific References | n/a |