CDH1 / E Cadherin Antibody from LSBio

Search, find, compare suppliers for anti-CDH1 / E Cadherin antibody, protein, ELISA kits.

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Antigenic SpecificityCDH1 / E Cadherin
ClonerCDH1/1525
Host SpeciesRecombinant Mouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein A/G purified
Size100 µg
Concentrationn/a
ApplicationsIF, IHC-P, WB
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DescriptionSpecificity: Recognizes a protein of 120-80 kDa , identified as E-cadherin. Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as beta-catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combination with p120 Catenin, it is useful for the differentiation between ductal (E-cadherin +) and lobular (E-cadherin -) breast carcinomas. It may also help in diagnosis of mesothelioma. Does not react with: Mouse, Rat
Immunogenn/a
Other NamesCDH1, CD324, CDHE, Cell-CAM 120/80, E Cadherin, E-Cadherin, ECAD, Epithelial cadherin, Arc-1, UVO, Cadherin-1, CAM 120/80, CD324 antigen, LCAM, Uvomorulin
Gene, Accession #CDH1, Gene ID: 999
Catalog #LS-B16237-100
Price$495
Order / More InfoCDH1 / E Cadherin Antibody from LSBio
Product Specific Referencesn/a
LSBio
LSBio
LSBio
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