IGF1R / IGF1 Receptor Antibody from LSBio

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Antigenic SpecificityIGF1R / IGF1 Receptor
Clone1H7
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size50 µg
Concentrationn/a
ApplicationsFlo, IHC, IHC-P, WB
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DescriptionSpecificity: Recognizes human CD221, a 155kD receptor tyrosine kinase, also known as Insulin-like growth factor I receptor (IGF-I Receptor). CD221 is composed of two extracellular alpha-subunits and two transmembrane beta-subunits. Recognizes an epitope in the alpha subunits of CD221, demonstrated by Western blotting. CD221 is expressed in a range of tissues, including kidney, liver, placenta, mammary gland, brain, ovary and skin. The ligands for CD221 include IGF-I and IGF-II, which bind to CD221 and activate tyrosine kinase activity, resulting in phosphorylation of several intracellular signalling proteins. Clone 1H7 is reported to partially block binding of IGF-I and IGF-II to CD221.
Immunogenn/a
Other NamesIGF1R, CD221 antigen, CD221, IGF1 Receptor, IGFR, IGF-I receptor, Soluble IGF1R variant 1, Soluble IGF1R variant 2, Type 1 IGF receptor, IGFIR, JTK13
Gene, Accession #IGF1R, Gene ID: 3480
Catalog #LS-B2613-50
Price$460
Order / More InfoIGF1R / IGF1 Receptor Antibody from LSBio
Product Specific Referencesn/a
LSBio
LSBio
LSBio
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