BCL6, aa256-389 Antibody from LSBio

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Antigenic SpecificityBCL6, aa256-389
ClonerBCL6/1718
Host SpeciesRecombinant Mouse
Reactive Specieshuman
IsotypeIgG1,k
FormatProtein A/G purified
Size100 µg
Concentrationn/a
ApplicationsIHC-P
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DescriptionSpecificity: Recognizes a protein of 95 kDa , which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( L&H ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Immunogenn/a
Other NamesBCL6, BCL6A, BCL-5, BCL5, Protein LAZ-3, LAZ3, ZBTB27, ZNF51, B-cell CLL/lymphoma 6, B-cell lymphoma 5 protein, B-cell lymphoma 6 protein, BCL-6, Zinc finger protein 51
Gene, Accession #BCL6, Gene ID: 604
Catalog #LS-C751349-100
Price$560
Order / More InfoBCL6, aa256-389 Antibody from LSBio
Product Specific Referencesn/a
LSBio
LSBio
LSBio
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