H2AFX / H2AX, C-terminus Antibody from LSBio

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Antigenic SpecificityH2AFX / H2AX, C-terminus
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size50 µg
Concentrationn/a
ApplicationsIF, IHC, IHC-P, WB
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DescriptionSpecificity: Recognizes human histone H2AX. H2AX comprises approximately 2-25% of the histone H2A pool in mammalian cells. The extended C-terminal tail of H2AX contains a serine (Ser139) embedded in an conserved SQE motif, which is rapidly phosphorylated at sites of double strand breaks and stalled replication forks. Phosphorylated H2AX may serve to recruit other repair proteins to the site of DNA damage. H2AX has been implicated in both homologous recombination and nonhomologous end joining DNA repair pathways.
Immunogenn/a
Other NamesH2AFX, H2AX, Histone H2A.x, H2A.X, H2A histone family, member X, H2AX histone
Gene, Accession #H2AFX, Gene ID: 3014
Catalog #LS-B3282-50
Price$485
Order / More InfoH2AFX / H2AX, C-terminus Antibody from LSBio
Product Specific Referencesn/a
LSBio
LSBio
LSBio
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