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Antigenic Specificity | FBXO3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, human |
Isotype | n/a |
Format | Protein G purified |
Size | 50 µg |
Concentration | n/a |
Applications | ELISA, IF, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation. |
Immunogen | n/a |
Other Names | FBXO3, F-box protein 3, F-box protein FBX3, F-box only protein 3, FBA, FBX3 |
Gene, Accession # | FBXO3, Gene ID: 26273 |
Catalog # | LS-C502157-50 |
Price | $294 |
Order / More Info | FBXO3 Antibody from LSBio |
Product Specific References | n/a |