BCL2 / Bcl-2 Antibody from LSBio

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Antigenic SpecificityBCL2 / Bcl-2
ClonerBCL2/782
Host SpeciesRecombinant Mouse
Reactive Specieshuman
IsotypeIgG1,k
FormatProtein A/G purified
Size100 µg
Concentrationn/a
ApplicationsFlo, IF, IHC-P, WB
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DescriptionSpecificity: This antibody recognizes a protein of 25-26 kDa , identified as the bcl-2alpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2alpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
Immunogenn/a
Other NamesBCL2, Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2, PPP1R50
Gene, Accession #BCL2, Gene ID: 596
Catalog #LS-B16222-100
Price$495
Order / More InfoBCL2 / Bcl-2 Antibody from LSBio
Product Specific Referencesn/a
LSBio
LSBio
LSBio
An Absolute Biotech Company
2 Shaker Road, Unit B101
Shirley MA 01464
P: 206-374-1102
P: 866-819-4732 (toll free N. America)
F: 206-577-4565

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