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Antigenic Specificity | GAPDH |
Clone | 6C5 |
Host Species | Mouse |
Reactive Species | rabbit |
Isotype | IgG1 |
Format | Protein A purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA, IF, IHC, IHC-Fr, IHC-P, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyze the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin. |
Immunogen | n/a |
Other Names | GAPDH, A1 40 kd subunit, Activator 1 40 kd subunit, G3PD, GAPD, G3pdh, Rfc40, Rf-c 40 kd subunit |
Gene, Accession # | GAPDH, Gene ID: 2597 |
Catalog # | LS-B11003-100 |
Price | $485 |
Order / More Info | GAPDH Antibody from LSBio |
Product Specific References | n/a |