SELL / L-Selectin / CD62L Antibody from LSBio
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|---|---|
| Antigenic Specificity | SELL / L-Selectin / CD62L |
| Clone | FMC46 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flo, IHC, IHC-Fr, IHC-P, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Recognizes human CD62L, also known a L-selectin, a 74-95kD member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation. |
| Immunogen | n/a |
| Other Names | SELL, CD62L, CD62L antigen, LAM-1, LAM1, LECAM1, LEU8, Leukocyte adhesion molecule 1, Lyam-1, LSEL, gp90-MEL, HLHRc, PLNHR, L-selectin, Leu-8, Selectin L, LNHR, LYAM1, Lymph node homing receptor, Lymphocyte adhesion molecule 1, TQ1, Pln homing receptor, CD26L |
| Gene, Accession # | SELL, Gene ID: 6402 |
| Catalog # | LS-C43268-0.1 |
| Price | $378 |
| Order / More Info | SELL / L-Selectin / CD62L Antibody from LSBio |
| Product Specific References | n/a |
LSBio
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