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Antigenic Specificity | CD300a (LMIR1), Mouse |
Clone | REA573 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 9 µg in 300 µL |
Concentration | 1:10 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD300a (LMIR1) Antibody, anti-mouse, APC, REAfinity™. Clone REA573 recognizes the mouse CD300a antigen, a type I transmembrane protein of the immunoglobulin superfamily, also known as leukocyte mono-Ig-like receptor1 (LMIR1) or inhibitory receptor protein 60 (IRp60). CD300a plays an important regulatory role in cell signaling and immune responses. It is expressed on monocytes, macrophages, neutrophils, mast cells, NK cells, dendritic cells, and on subsets of T and B lymphocytes. | Additional information: Clone REA573 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | CLM-8, Lmir1, MAIR-I, MAIR-Ia, MMAC8, Pigr4, Mcpir1, MAIR-1, IRp60, CMRF-35H |
Gene, Accession # | Gene ID: 217303 |
Catalog # | 130-109-092 |
Price | $61 |
Order / More Info | CD300a (LMIR1), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Bachelet, I. et al. (2005) The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells. J Immunol 175 (12): 7989-7995. | Yotsumoto, K. et al. (2003) Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation. J. Exp. Med. 198 (2): 223-233. | Cantoni, C. et al. (1999) Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells. Eur. J. Immunol. 29 (10): 3148-3159. | Kumagai, H. et al. (2003) Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells. Biochem. Biophys. Res. Commun. 307 (3): 719-729. |