CD86, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD86, Rat |
| Clone | 24F |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1κ |
| Format | allophycocyanin (APC) conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD86 Antibody, anti-rat, APC. Clone 24F recognizes the rat antigen CD86, also known as B7-2, which is a member of the B7 family of costimulatory molecules. In addition to CD80 (B7-1) , CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). It is expressed by germinal center B cells and weakly expressed on antigen presenting cells, such as macrophages and dendritic cells. Its expression is upregulated on B cells through a variety of surface stimuli including LPS. CD86 plays a critical role in the early events of T cell activation and costimulation of naive T cells as well as autoantibody and T?2-mediated Ig production. |
| Immunogen | n/a |
| Other Names | B7-2, B70 |
| Gene, Accession # | Gene ID: 56822 |
| Catalog # | 130-109-177 |
| Price | $61 |
| Order / More Info | CD86, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Bluestone, J. A. et al. (1995) New perspectives of CD28-B7-mediated T cell costimulation. Immunity 2 (6): 555-559. | Maeda, K. et al. (1997) Characterization of rat CD80 and CD86 by molecular cloning and mAb. Int. Immunol. 9 (7): 993-1000. | Damoiseaux, J. G. et al. (1998) Costimulatory molecules CD80 and CD86 in the rat; tissue distribution and expression by antigen-presenting cells. J. Leukoc. Biol. 64 (6): 803-809. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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