Villin, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Villin, Human |
| Clone | REAL815 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Villin Antibody, anti-human, PE, REAdye_lease™. Clone REAL815 is an antibody fragment derived from the full Villin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL815 recognizes human Villin protein, also known as Villin-1, a member of a family of calcium-regulated actin-binding proteins encoded by the VIL1 gene. This protein represents a dominant part of the brush border cytoskeleton and plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Villin regulates the intestinal epithelial cell morphology, cell invasion, cell migration and apoptosis and enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, chemotaxis and wound repair. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
| Immunogen | n/a |
| Other Names | Villin-1, VIL1, VIL |
| Gene, Accession # | n/a |
| Catalog # | 130-130-344 |
| Price | $520 |
| Order / More Info | Villin, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Wang, Y. et al. (2008) A novel role for villin in intestinal epithelial cell survival and homeostasis. J. Biol. Chem. 283 (14): 9454-9464. | Srivatsa, S. et al. (2017) EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patient. Gastroenterology 153 (1): 178-190. | Izdebska, M. et al. (2020) Involvement of Actin and Actin-Binding Proteins in Carcinogenesis. Cells 9 (10): 2245. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG