CD68, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD68, Mouse |
| Clone | FA-11 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD68 Antibody, anti-mouse, APC. The monoclonal antibody FA-11 recognizes mouse CD68, also known as macrosialin, which is a heavily glycosylated type I transmembrane protein of the LAMP (lysosomal-associated membrane protein) family. It is expressed on tissue macrophages, langerhans cells and at a low density on dendritic cells. Murine CD68 is predominantly intracellular but it is reported that 10-15% of CD68 is expressed on the cell surface as well. Macrosialin functions as a macrophage receptor for oxidized low density lipoprotein. |
| Immunogen | n/a |
| Other Names | Lamp4, SCARD1, gp110, macrosialin |
| Gene, Accession # | Gene ID: 12514 |
| Catalog # | 130-102-585 |
| Price | $93 |
| Order / More Info | CD68, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Ramprasad, M. P. et al. (1996) Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. Proc. Natl. Acad. Sci. U.S.A. 93: 14833-14838. | Kurushima, H. et al. (2000) Surface expression and rapid internalization of macrosialin (mouse CD68) on elicited mouse peritoneal macrophages. J. Leukoc. Biol. 67: 104-108. | Smith, M. J. et al. (1987) Differential expression of murine macrophage surface glycoprotein antigens in intracellular membranes. J. Cell. Sci. 87: 113-119. | Jungblut, M. et al. (2012) Isolation and characterization of living primary astroglial cells using the new GLAST-specific monoclonal antibody ACSA-1. Glia 60 (6): 894-907. | G. Kantzer, C. et al. (2017) Anti-ACSA-2 defines a novel monoclonal antibody for prospective isolation of living neonatal and adult astrocytes. Glia 65 (6): 990-1004. | Batiuk, M. Y. et al. (2017) An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody. J. Biol. Chem. 292 (21): 8874-8891. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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