LT-βR, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | LT-βR, Mouse |
| Clone | REA416 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | LT-βR Antibody, anti-mouse, APC, REAfinity™. Clone REA416 recognizes the mouse lymphotoxin β receptor (LT-βR) antigen, a 61 kD single-pass type I membrane protein which is also known as tumor necrosis factor receptor superfamily member 3 (Tnfrsf3). LT-βR is a member of the TNF receptor family that play a role in the development and organization of lymphoid tissues. Membrane-bound lymphotoxin LTα1LTβ2 and LIGHT (TNFSF14) are members of the TNF family of cytokines. Both are primarily expressed on lymphocytes and each can deliver signals through LT-βR. In contrast, LT-βR is primarily expressed on epithelial, stromal and myeloid cells, but not lymphocytes, suggesting that it may participate in the communication between lymphocytes and surrounding epithelial and stromal cells. | Additional information: Clone REA416 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Ltbr, Tnfcr, LTbetaR, Ltar, CD18, LTBR, Tnfrsf3 |
| Gene, Accession # | Gene ID: 17000 |
| Catalog # | 130-106-637 |
| Price | $59 |
| Order / More Info | LT-βR, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Force, W. R. et al. (1995) Mouse lymphotoxin-beta receptor. Molecular genetics, ligand binding, and expression. J Immunol 155 (11): 5280-5288. | Lkhagvasuren, E. et al. (2013) Lymphotoxin β receptor regulates the development of CCL21-expressing subset of postnatal medullary thymic epithelial cells. J Immunol 190 (10): 5110-5117. | Onder, L. et al. (2013) Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation. J. Exp. Med. 210 (3): 465-473. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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